Three key defenders are on the treatment table ahead of the May 25 clash with Tipperary in Fermoy - Shane Gallagher, Pa Ranahan and Andrew Lane.
Gallagher and Lane are both suffering with hamstring injuries, while Ranahan has a knee injury.
"We are hoping that they will all have cleared up," said Limerick manager, Mickey Ned O'Sullivan this week.
Adding to the injury headache, other defensive options; Conor Mullane and Pat Ahern have been unable to take a full part in recent training sessions.
Micheal Reidy and Jim O'Donovan are also on the treatment table at present, while Ian Ryan and Conal Crowley are trying to shake off the effects of the flu.
"We havent an awful lot of backs left in our squad," conceded O'Sullivan.
Limerick played Clare in a challenge game last week and this Wednesday night completed their preparations with a game against Waterford.
"The Clare game was a good workout - the ball was moving fast, just like championship pace."
The Limerick team to play Tipperary will be selected after training next Sunday evening.
"I have something in my head, but we will just have to wait and see with the injuries. The team has evolved itself - some players have played themselves onto the team and others have played themselves off. Overall, I think we have put together a strong panel."
O'Sullivan says that he has seen a fresh impetus to his squad since the end of the league campaign, which saw Limerick avoid relegation with a final round win over Leitrim.
"The players showed great bottle when it was needed," he said. "We were in the most competitive league - regardless of what division it was. We had a tough league with injuries, suspensions and the dual players, but it was a great test and we used every member of our squad."
One change since the end of the league is that former Clare senior football manager, Donie Buckley has been drafted in to take a number of training sessions.
"Donie takes some sessions when Michael McGeehin cant make it. Donie is very professional and has great experience - he brings a new voice into the dressing room as well. I think that we are in a healthy position," stated the manager.
Mickey Ned has seen Tipperary in action.
"They have made a lot of progress under John Evans and after getting promoted they will play in Division Three next season. They will have gained confidence from getting promoted," he stated.